ML221
ML221 is a potent apelin /APJ functional antagonist, inhibiting apelin-13-mediated activation of APJ, with IC50s of 0.70 μM in the cAMP assay, and 1.75 μM in the β-arrestin assay, and EC80 of 10 nM in both assays.
Product Specifications
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
385.35
Molecular Formula
C17H11N3O6S
Notes
Research use only, not for human use.
Receptor
APJ
CAS Number
877636-42-5
Available Sizes
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