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ML221

ML221 is a potent apelin /APJ functional antagonist, inhibiting apelin-13-mediated activation of APJ, with IC50s of 0.70 μM in the cAMP assay, and 1.75 μM in the β-arrestin assay, and EC80 of 10 nM in both assays.

Product Specifications

CAS Number

877636-42-5

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

385.35

Molecular Formula

C17H11N3O6S

Notes

Research use only, not for human use.

Receptor

APJ

Available Sizes

Frequently Asked Questions

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