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TAK-285

TAK-285 is a novel dual HER2 and EGFR (HER1) inhibitor with IC50 of 17 nM and 23 nM, >10-fold selectivity for HER1/2 than HER4, less potent to MEK1/5, c-Met, Aurora B, Lck, CSK etc. Phase 1.

Product Specifications

CAS Number

871026-44-7

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

547.96

Molecular Formula

C26H25ClF3N5O3

Notes

Research use only, not for human use.

Receptor

Aurora B| EGFR/HER1| HER2| HER4| MEK1

Available Sizes

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