TAK-285
TAK-285 is a novel dual HER2 and EGFR (HER1) inhibitor with IC50 of 17 nM and 23 nM, >10-fold selectivity for HER1/2 than HER4, less potent to MEK1/5, c-Met, Aurora B, Lck, CSK etc. Phase 1.
Product Specifications
CAS Number
871026-44-7
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
547.96
Molecular Formula
C26H25ClF3N5O3
Notes
Research use only, not for human use.
Receptor
Aurora B| EGFR/HER1| HER2| HER4| MEK1
Available Sizes
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