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OSI-420

OSI-420 (Desmethyl Erlotinib, CP-473420) is an active metabolite of erlotinib which is an orally active EGFR tyrosin kinase inhibitor with IC50 of 2 and 20 nM for human EGFR and EGFR autophosphorylation in tumor cells.

Product Specifications

CAS Number

183320-51-6

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

415.87

Molecular Formula

C21H21N3O4·HCl

Notes

Research use only, not for human use.

Receptor

EGFR

Available Sizes

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