WYE-687
WYE-687 is an ATP-competitive and selective inhibitor of mTOR with IC50 of 7 nM; blocks mTORC1/pS6K (T389) and mTORC2/P-AKT (S473) but no effect observed on P-AKT (T308) .
Product Specifications
CAS Number
1062161-90-3
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
528.61
Molecular Formula
C28H32N8O3
Notes
Research use only, not for human use.
Receptor
MTOR , PI3Kα , PI3Kγ , p38α , Src
Available Sizes
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