VX-809
VX-809 (Lumacaftor, VRT 826809) is a potent CFTR corrector that increases F508del-CFTR-mediated chloride transport amd improves F508del-CFTR maturation in FRT cells with EC50 of 0.1 and 0.5 uM, respectively.
Product Specifications
CAS Number
936727-05-8
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
452.41
Molecular Formula
C24H18F2N2O5
Notes
Research use only, not for human use.
Receptor
F508del-CFTR
Available Sizes
Curated Selection
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