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Crisdesalazine

Crisdesalazine (AAD-2004, AAD2004) is a derivative of aspirin that inhibits microsomal PGE (2) synthase-1 (mPGES-1) activity in response to both LPS-treated BV2 cell with IC50 of 230 nM and recombinant human mPGES-1 protein with IC50 of 249 nM in vitro.

Product Specifications

CAS Number

927685-43-6

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

325.287

Molecular Formula

C16H14F3NO3

Notes

Research use only, not for human use.

Receptor

PGE synthase

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(S) -2- ((((9H-Fluoren-9-yl) methoxy) carbonyl) amino) -4- (((2R,3R,4R,5S,6R) -3-acetamido-4,5-diacetoxy-6- (acetoxymethyl) tetrahydro-2H-pyran-2-yl) amino) -4-oxobutanoic acid
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