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LY2603618

A potent and selective small molecule inhibitor of Chk1 (IC50= 7 nM) ; promotes impaired DNA synthesis and elevates H2A.X phosphorylation indicative of DNA damage and premature entry into mitosis.

Product Specifications

CAS Number

911222-45-2

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

436.303

Molecular Formula

C18H22BrN5O3

Notes

Research use only, not for human use.

Receptor

Chk1|PDK1

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