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AT-7519 hydrochloride

A potent CDK2 inhibitor with IC50 of 47 nM; also inhibits CDK1/4/5 with IC50 of 190/67/18 nM and shows selectivity over some kinases (Aurora A, IR kinase, MEK, PDK1, c-Abl, IC50>10 uM) .

Product Specifications

CAS Number

902135-91-5

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

418.7054

Molecular Formula

C16H18Cl3N5O2

Notes

Research use only, not for human use.

Receptor

CDK2/CyclinA|CDK4/CyclinD1|CDK5/p35|CDK9/CyclinT|GSK-3β

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