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Ivacaftor

Ivacaftor (VX-770, VX770) is a potent, orally bioavailable CFTR potentiator, increases G551D- and F508del CFTR-mediated Cl- secretion with EC50 of 100 nM.

Product Specifications

CAS Number

873054-44-5

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

392.4907

Molecular Formula

C24H28N2O3

Notes

Research use only, not for human use.

Receptor

F508del-CFTR|G551D-CFTR

Available Sizes

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