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Afatinib dimaleate

An irreversible, dual EGFR/HER2 inhibitor with IC50 of 0.5/0.4/10/14 nM for wt EGFR/EGFR L858R/EGFR L858R+T790M/HER2 respectively.

Product Specifications

CAS Number

850140-73-7

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

718.0827

Molecular Formula

C32H33ClFN5O11

Notes

Research use only, not for human use.

Receptor

EGFR (L858R) |EGFR (L858R/T790M) |EGFR (wt) |HER2

Available Sizes

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