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Afatinib

An irreversible, dual EGFR/HER2 inhibitor with IC50 of 0.5/0.4/10/14 nM for wt EGFR/EGFR L858R/EGFR L858R+T790M/HER2 respectively.

Product Specifications

CAS Number

850140-72-6

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

485.9384

Molecular Formula

C24H25ClFN5O3

Notes

Research use only, not for human use.

Receptor

EGFR

Available Sizes

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