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Tofacitinib citrate

A potent, specific, orally active inhibitor of JAK3 with IC50 of 1 nM in cell-free assays; displays 20- to 100-fold less potency for JAK2 and JAK1 (IC50=20 nM and 112 nM, respectively) .

Product Specifications

CAS Number

540737-29-9

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

504.4931

Molecular Formula

C22H28N6O8

Notes

Research use only, not for human use.

Receptor

JAK1|JAK2|JAK3|Lck|ROCK2

Available Sizes

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