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Vandetanib

Vandetanib is an orally bioavailable 4-anilinoquinazoline. Vandetanib selectively inhibits the tyrosine kinase activity of vascular endothelial growth factor receptor 2 (VEGFR2), thereby blocking VEGF-stimulated endothelial cell proliferation and migration and reducing tumor vessel permeability.

Product Specifications

CAS Number

443913-73-3

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

475.31

Molecular Formula

C22H24BrFN4O2

Notes

Research use only, not for human use.

Receptor

EGFR| VEGFR2| VEGFR3

Available Sizes

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