Semagacestat
A potent γ-secretase inhibitor that inhibits β-amyloid Aβ42, Aβ38 and Aβ40 with IC50 of 10.9, 12 and 12.1 nM, respectively.
Product Specifications
CAS Number
425386-60-3
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
361.4354
Molecular Formula
C19H27N3O4
Notes
Research use only, not for human use.
Receptor
Notch|γsecretase (Aβ38) |γsecretase (Aβ40) |γsecretase (Aβ42)
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