SU-9516
A selective CDK2 inhibitor with IC50 of 22 nM; shows less potent for CDK1/CDK4 (IC50=40/200 nM), no inhibition on PKC, EGFR, p38MAPK; decreases the phosphorylation of pRb, and increases caspase-3 activation.
Product Specifications
CAS Number
377090-84-1
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
241.2453
Molecular Formula
C13H11N3O2
Notes
Research use only, not for human use.
Receptor
CDK1|CDK2|CDK4|p38|PKC
Available Sizes
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