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SU-9516

A selective CDK2 inhibitor with IC50 of 22 nM; shows less potent for CDK1/CDK4 (IC50=40/200 nM), no inhibition on PKC, EGFR, p38MAPK; decreases the phosphorylation of pRb, and increases caspase-3 activation.

Product Specifications

CAS Number

377090-84-1

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

241.2453

Molecular Formula

C13H11N3O2

Notes

Research use only, not for human use.

Receptor

CDK1|CDK2|CDK4|p38|PKC

Available Sizes

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