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SMER-28

A small-molecule enhancer/inducer of Autophagy; decreases the levels of Aβ peptide (EC50=10 uM) and APP-CTF (EC50 of 20 uM) in a γ-secretase-independent manner in primary neuronal cultures, Atg5, Beclin1 and Ulk1 are shown to be involved in the degradation of Aβ and APP-CTF.

Product Specifications

CAS Number

307538-42-7

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

264.1212

Molecular Formula

C11H10BrN3

Notes

Research use only, not for human use.

Receptor

Autophagy

Available Sizes

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