SMER-28
A small-molecule enhancer/inducer of Autophagy; decreases the levels of Aβ peptide (EC50=10 uM) and APP-CTF (EC50 of 20 uM) in a γ-secretase-independent manner in primary neuronal cultures, Atg5, Beclin1 and Ulk1 are shown to be involved in the degradation of Aβ and APP-CTF.
Product Specifications
CAS Number
307538-42-7
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
264.1212
Molecular Formula
C11H10BrN3
Notes
Research use only, not for human use.
Receptor
Autophagy
Available Sizes
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