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Gefitinib-based PROTAC 3

Gefitinib-based PROTAC 3 is a VHL-recruiting PROTAC that induces the degradation of EGFR and EGFR mutants with DC50 of 11.7 nM and 22.3 nM for HCC827 cell (Exon 19 del) and H3255 cell (L858R) .

Product Specifications

CAS Number

2230821-27-7

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

934.522

Molecular Formula

C47H57ClFN7O8S

Notes

Research use only, not for human use.

Receptor

PROTAC

Available Sizes

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