JNJ-55308942

JNJ-55308942 is a novel highly potent P2X7 antagonist with Ki of 1.0 and 6.5 nM for rat and human hP2X7, demonstrates significant activity against a panel of related P2X receptors (P2X1, P2X2, P2X3, P2X2/3, and P2X4; also shows insignificant inhibition of nine CYP isoforms (IC50>15 uM) .

Product Specifications

CAS Number

2166558-11-6

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

425.323

Molecular Formula

C17H12F5N7O

Notes

Research use only, not for human use.

Receptor

P2X Receptor

Available Sizes

Curated Selection

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