JNJ-55308942
JNJ-55308942 is a novel highly potent P2X7 antagonist with Ki of 1.0 and 6.5 nM for rat and human hP2X7, demonstrates significant activity against a panel of related P2X receptors (P2X1, P2X2, P2X3, P2X2/3, and P2X4; also shows insignificant inhibition of nine CYP isoforms (IC50>15 uM) .
Product Specifications
CAS Number
2166558-11-6
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
425.323
Molecular Formula
C17H12F5N7O
Notes
Research use only, not for human use.
Receptor
P2X Receptor
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