VX-745

A potent and selective p38α kinase inhibitor with IC50 of 9 nM; shows 20-fold selectivity for p38α over p38β (Ki=220 nM) and no significant inhibition for MAP kinases (with the exception of MKK6) .

Product Specifications

CAS Number

209410-46-8

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

436.2621

Molecular Formula

C19H9Cl2F2N3OS

Notes

Research use only, not for human use.

Receptor

P38α|p38β

Available Sizes

Curated Selection

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