VX-745
A potent and selective p38α kinase inhibitor with IC50 of 9 nM; shows 20-fold selectivity for p38α over p38β (Ki=220 nM) and no significant inhibition for MAP kinases (with the exception of MKK6) .
Product Specifications
CAS Number
209410-46-8
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
436.2621
Molecular Formula
C19H9Cl2F2N3OS
Notes
Research use only, not for human use.
Receptor
P38α|p38β
Available Sizes
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