CCT251545
CCT251545 is a potent, orally bioavailable inhibitor of Wnt signaling with IC50 of 5 nM, also is a potent and selective chemical probe for CDK8 and CDK19 with >100-fold selectivity over 291 other kinases; potently inhibits reporter-based readouts of basal WNT pathway activity in LS174T and SW480 cells in the absence of WNT ligand with IC50 of 23 and 190 nM, respectively.
Product Specifications
CAS Number
1661839-45-7
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
421.9225
Molecular Formula
C23H24ClN5O
Notes
Research use only, not for human use.
Receptor
CDK
Available Sizes
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