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CCT251545

CCT251545 is a potent, orally bioavailable inhibitor of Wnt signaling with IC50 of 5 nM, also is a potent and selective chemical probe for CDK8 and CDK19 with >100-fold selectivity over 291 other kinases; potently inhibits reporter-based readouts of basal WNT pathway activity in LS174T and SW480 cells in the absence of WNT ligand with IC50 of 23 and 190 nM, respectively.

Product Specifications

CAS Number

1661839-45-7

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

421.9225

Molecular Formula

C23H24ClN5O

Notes

Research use only, not for human use.

Receptor

CDK

Available Sizes

Frequently Asked Questions

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