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THZ-1

A potent, selective, covalent CDK7 inhibitor with IC50 of 3.2 nM; also weakly inhibits CDK12 with IC50 of 250 nM; displays broad-based activity a subset of cancer cell lines with IC50s of <200 nM.

Product Specifications

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

566.0527

Molecular Formula

C31H28ClN7O2

Notes

Research use only, not for human use.

Receptor

CDK7

CAS Number

1604810-83-4

Available Sizes

Curated Selection

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