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PFM01

PFM01 (SML1735) is a small molecule that specifically inhibits endonuclease, but not exonuclease activity of MRE11, inhibits dsDNA end resection in A549 cells with IC50 of 50-75 uM, blocks the ssDNA-binding path toward the catalytic metal ions and disrupts endonuclease activity.

Product Specifications

CAS Number

1558598-41-6

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

293.399

Molecular Formula

C14H15NO2S2

Notes

Research use only, not for human use.

Receptor

DNA Repair Protein

Available Sizes

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