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AVL-292

AVL-292 (Spebrutinib, CC-292) is a highly selective, covalent Btk inhibitor with IC50 of <1 nM; also less potently inhibits Yes, c-Src, Brk, Lyn, and Fyn with IC50s of 723 nM, 1.729 uM, 2.43 uM, 4.4 uM, and 7.15 uM, rspectively.

Product Specifications

CAS Number

1202757-89-8

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

423.4402

Molecular Formula

C22H22FN5O3

Notes

Research use only, not for human use.

Receptor

BRK|BTK|c-Src|Lyn|Yes

Available Sizes

Frequently Asked Questions

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