AVL-292
AVL-292 (Spebrutinib, CC-292) is a highly selective, covalent Btk inhibitor with IC50 of <1 nM; also less potently inhibits Yes, c-Src, Brk, Lyn, and Fyn with IC50s of 723 nM, 1.729 uM, 2.43 uM, 4.4 uM, and 7.15 uM, rspectively.
Product Specifications
CAS Number
1202757-89-8
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
423.4402
Molecular Formula
C22H22FN5O3
Notes
Research use only, not for human use.
Receptor
BRK|BTK|c-Src|Lyn|Yes
Available Sizes
Frequently Asked Questions
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