CCT 137690
A potent, orally bioavailable Aurora kinases inhibitor with IC50 of 15/25/19 nM for Aurora A/B/C; displays antiproliferative activity in a range of human tumor cell lines, including SW620 colon carcinoma (GI50=0.30 uM) and A2780 ovarian cancer cell line (GI50=0.14 uM) .
Product Specifications
CAS Number
1095382-05-0
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
551.4813
Molecular Formula
C26H31BrN8O
Notes
Research use only, not for human use.
Receptor
AuroraA|AuroraB|AuroraC
Available Sizes
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