Neboglamine

Neboglamine (CR-2249; XY-2401) is a modulator for N-methyl-D-aspartate (NMDA) receptor. Neboglamine increases the levels of fos-like immunoreactivity (FLI) -positive cells in the prefrontal cortex, nucleus accumbens, and lateral septal nucleus in rat models, .restores NMDA (HY-17551) -mediated neurotransmitter release, and inhibits phencyclidine-induced hyperlocomotion[1].

Product Specifications

CAS Number

[163000-63-3]

Product Name Alternative

CR-2249; XY-2401

UNSPSC

12352211

Hazard Statement

H302

Target

IGluR

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/neboglamine.html

Smiles

OC(CC[C@H](N)C(NC1CCC(C)(CC1)C)=O)=O

Molecular Formula

C13H24N2O3

Molecular Weight

256.34

Precautions

P264-P270-P330-P501

References & Citations

[1]Chiusaroli R, et al., Antipsychotic-like effects of the N-methyl-D-aspartate receptor modulator neboglamine: an immunohistochemical and behavioural study in the rat. Pharmacol Res. 2010 May;61 (5) :430-6.