MAT2A inhibitor 6
MAT2A inhibitor 6 (Compound 3N-h) is a specific MAT2A inhibitor with oral activity and yellow fluorescence (IC50=26 nM), capable of visualizing MAT2A both in vitro and in vivo (λex = 430 nm, λem = 585 nm) . MAT2A inhibitor 6 can induce apoptosis and has anticancer activity, which can be used in cancer research[1].
Product Specifications
CAS Number
2447686-21-5
UNSPSC
12171500
Target
Apoptosis; Fluorescent Dye; Methionine Adenosyltransferase (MAT)
Type
Dye Reagents
Related Pathways
Apoptosis; Epigenetics; Metabolic Enzyme/Protease; Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mat2a-inhibitor-6.html
Smiles
O=C1C(C2=CC=C(OC(F)F)C=C2)=C3C(C=CC(OCC)=N3)=NN1C4=CC5=CN(C)N=C5C=C4
Molecular Formula
C24H19F2N5O3
Molecular Weight
463.44
References & Citations
[1]Wang Z, et al. Computer-aided design of a fluorescent MAT2A inhibitor for visualized cancer synthetic lethality. Bioorg Chem. 2024 Sep;150:107582.
Shipping Conditions
Room temperature
Scientific Category
Dye Reagents
Clinical Information
No Development Reported
Frequently Asked Questions
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