Biflorin
Biflorin has antimicrobial, antitumor, antiinflammatory and antimutagenic activities. Biflorin is found in the roots of Capraria biflora L[1][2][3].
Product Specifications
CAS Number
89701-85-9
UNSPSC
12352005
Target
Apoptosis; STAT
Type
Natural Products
Related Pathways
Apoptosis; JAK/STAT Signaling; Stem Cell/Wnt
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/biflorin.html
Purity
99.54
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1C=C(C)OC2=CC(O)=C([C@H]3[C@@H]([C@H]([C@@H]([C@@H](CO)O3)O)O)O)C(O)=C12
Molecular Formula
C16H18O9
Molecular Weight
354.31
References & Citations
[1]Vasconcellos MC, et al. The in-vitro and in-vivo inhibitory activity of biflorin in melanoma. Melanoma Res. 2011 Apr;21 (2) :106-14.|[2]Lee HH, et al. Biflorin, Isolated from the Flower Buds of Syzygium aromaticum L., Suppresses LPS-Induced Inflammatory Mediators via STAT1 Inactivation in Macrophages and Protects Mice from Endotoxin Shock. J Nat Prod. 2016 Apr 22;79 (4) :711-20.|[3]Vasconcellos MC, et al. Evaluation of the cytotoxic and antimutagenic effects of biflorin, an antitumor 1,4 o-naphthoquinone isolated from Capraria biflora L. Arch Toxicol. 2010 Oct;84 (10) :799-810.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
STAT1
Frequently Asked Questions
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