Biflorin

Biflorin has antimicrobial, antitumor, antiinflammatory and antimutagenic activities. Biflorin is found in the roots of Capraria biflora L[1][2][3].

Product Specifications

CAS Number

[89701-85-9]

UNSPSC

12352005

Target

Apoptosis; STAT

Type

Natural Products

Related Pathways

Apoptosis; JAK/STAT Signaling; Stem Cell/Wnt

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/biflorin.html

Purity

99.54

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C1C=C(C)OC2=CC(O)=C([C@H]3[C@@H]([C@H]([C@@H]([C@@H](CO)O3)O)O)O)C(O)=C12

Molecular Formula

C16H18O9

Molecular Weight

354.31

References & Citations

[1]Vasconcellos MC, et al. The in-vitro and in-vivo inhibitory activity of biflorin in melanoma. Melanoma Res. 2011 Apr;21 (2) :106-14.|[2]Lee HH, et al. Biflorin, Isolated from the Flower Buds of Syzygium aromaticum L., Suppresses LPS-Induced Inflammatory Mediators via STAT1 Inactivation in Macrophages and Protects Mice from Endotoxin Shock. J Nat Prod. 2016 Apr 22;79 (4) :711-20.|[3]Vasconcellos MC, et al. Evaluation of the cytotoxic and antimutagenic effects of biflorin, an antitumor 1,4 o-naphthoquinone isolated from Capraria biflora L. Arch Toxicol. 2010 Oct;84 (10) :799-810.