Aprinocarsen (sodium)
Aprinocarsen (ISIS 3521) sodium, a specific antisense oligonucleotide inhibitor of protein kinase C-alpha (PKC-α) . Aprinocarsen sodium is a 20-mer oligonucleotide, it regulates cell differentiation and proliferation. Aprinocarsen sodium inhibits the growth of human tumor cell lines in nude mice. Aprinocarsen sodium shows the value as a chemotherapeutic compound of human cancers[1].
Product Specifications
CAS Number
[331257-53-5]
Product Name Alternative
ISIS 3521 (sodium)
UNSPSC
12352208
Target
PKC
Type
Oligonucleotides
Related Pathways
Epigenetics; TGF-beta/Smad
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/aprinocarsen-sodium.html
Purity
98.42
Solubility
H2O : 100 mg/mL (ultrasonic)
Smiles
[Aprinocarsen(sodium)]
Molecular Formula
C196H230N68Na19O105P19S19
Molecular Weight
6435.2 (free acid)
References & Citations
[1]https://pubmed.ncbi.nlm.nih.gov/8758918/
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
Available Sizes
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
