Neoseptin 3
Neoseptin 3 is a Toll-like receptor 4/myeloid differentiation factor 2 (mTLR4/MD-2) agonist with an EC50 of 18.5 μM.
Product Specifications
CAS Number
[1622863-21-1]
UNSPSC
12352005
Hazard Statement
H413
Target
Toll-like Receptor (TLR)
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Neoseptin_3.html
Purity
99.21
Solubility
DMSO : ≥ 100 mg/mL
Smiles
CC(C)(C)OC([C@H](CCC1=CC=CC=C1)NC(C2=CC(CCC3=CC=C(O)C=C3)=C(N)C=C2)=O)=O
Molecular Formula
C29H34N2O4
Molecular Weight
474.59
Precautions
H413
References & Citations
[1]Wang Y, et al. TLR4/MD-2 activation by a synthetic agonist with no similarity to LPS. Proc Natl Acad Sci U S A. 2016 Feb 16;113 (7) :E884-93.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
TLR4
Available Sizes
Curated Selection
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