2'-Deoxyadenosine-5'-monophosphate

2′-Deoxyadenosine 5′-monophosphate, a nucleic acid AMP derivative, is a deoxyribonucleotide found in DNA. 2′-Deoxyadenosine 5′-monophosphate can be used to study adenosine-based interactions during DNA synthesis and DNA damage[1].

Product Specifications

CAS Number

[653-63-4]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Endogenous Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/2-deoxyadenosine-5-monophosphate.html

Purity

99.60

Solubility

DMSO : 44.44 mg/mL (ultrasonic; warming; adjust pH to 7 with NH3·H2O; heat to 60°C)

Smiles

NC1=C2C(N([C@H]3C[C@H](O)[C@@H](COP(O)(O)=O)O3)C=N2)=NC=N1

Molecular Formula

C10H14N5O6P

Molecular Weight

331.23

Precautions

H302, H315, H319, H335

References & Citations

[1]Katsuya Narumi, et al. Mutual role of ecto-5'-nucleotidase/CD73 and concentrative nucleoside transporter 3 in the intestinal uptake of dAMP. PLoS One. 2019 Oct 21;14 (10) :e0223892.|[2]V Duarte, et al. Insertion of dGMP and dAMP during in vitro DNA synthesis opposite an oxidized form of 7,8-dihydro-8-oxoguanine. Nucleic Acids Res. 1999 Jan 15;27 (2) :496-502.