2-Iodoacetamide-d4
2-Iodoacetamide-d4 is the deuterium labeled 2-Iodoacetamide[1]. 2-Iodoacetamide (Iodoacetamide), an alkylating agent, is a commonly used agent for alkylation of cysteine during sample preparation for proteomics[2][3].
Product Specifications
CAS Number
[1219802-64-8]
Product Name Alternative
Iodoacetamide-d4
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
DNA Alkylator/Crosslinker
Type
Isotope-Labeled Compounds
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Others
Purity
99.90
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
IC([2H])([2H])C(N([2H])[2H])=O
Molecular Formula
C2D4INO
Molecular Weight
188.99
Precautions
H302, H315, H319, H335
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Peter G Hains, et al. The Impact of Commonly Used Alkylating Agents on Artifactual Peptide Modification. J Proteome Resq. 2017 Sep 1;16 (9) :3443-3447.|[3]J J LALICH. Iodoacetamide induced gastric ulcers in rats. Proc Soc Exp Biol Med. 1962 Apr109:905-8.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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