Decylubiquinone
Decylubiquinone is an analog of ubiquinone (coenzyme Q10) . Decylubiquinone blocks reactive oxygen species (ROS) production in response to glutathione depletion and inhibits activation of the mitochondrial permeability transition[1].
Product Specifications
CAS Number
[55486-00-5]
UNSPSC
12352211
Hazard Statement
H315, H319, H335
Target
Reactive Oxygen Species (ROS)
Type
Reference compound
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
Cancer-programmed cell death
Field of Research
Cancer; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/decylubiquinone.html
Concentration
77.53 mM * 400 μL in Ethanol
Purity
99.0
Solubility
10 mM in DMSO
Smiles
O=C1C(CCCCCCCCCC)=C(C(C(OC)=C1OC)=O)C
Molecular Formula
C19H30O4
Molecular Weight
322.44
Precautions
H315, H319, H335
References & Citations
[1]Jeffrey S Armstrong, et al. The Coenzyme Q10 analog decylubiquinone inhibits the redox-activated mitochondrial permeability transition: role of mitcohondrial [correction mitochondrial] complex III. J Biol Chem. 2003 Dec 5;278 (49) :49079-84.
Shipping Conditions
Blue Ice
Storage Conditions
Solution, -20°C, 2 years
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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