Decylubiquinone

Decylubiquinone is an analog of ubiquinone (coenzyme Q10) . Decylubiquinone blocks reactive oxygen species (ROS) production in response to glutathione depletion and inhibits activation of the mitochondrial permeability transition[1].

Product Specifications

CAS Number

[55486-00-5]

UNSPSC

12352211

Hazard Statement

H315, H319, H335

Target

Reactive Oxygen Species (ROS)

Type

Reference compound

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

Cancer-programmed cell death

Field of Research

Cancer; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/decylubiquinone.html

Concentration

77.53 mM * 400 μL in Ethanol

Purity

99.0

Solubility

10 mM in DMSO

Smiles

O=C1C(CCCCCCCCCC)=C(C(C(OC)=C1OC)=O)C

Molecular Formula

C19H30O4

Molecular Weight

322.44

Precautions

H315, H319, H335

References & Citations

[1]Jeffrey S Armstrong, et al. The Coenzyme Q10 analog decylubiquinone inhibits the redox-activated mitochondrial permeability transition: role of mitcohondrial [correction mitochondrial] complex III. J Biol Chem. 2003 Dec 5;278 (49) :49079-84.