Dde Biotin-PEG4-azide
Product Specifications
UNSPSC Description
Dde Biotin-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Dde Biotin-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Target Antigen
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dde-biotin-peg4-azide.html
Solubility
10 mM in DMSO
Smiles
O=C(NCCOCCOCCOCCOCC/C(NCCCN=[N+]=[N-])=C1C(CC(C)(C)CC\1=O)=O)CCCC[C@H]2SC[C@@]([C@@]2([H])N3)([H])NC3=O
Molecular Weight
695.87
References & Citations
[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-140916/Dde-Biotin-PEG4-azide-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-140916/
Clinical Information
No Development Reported
CAS Number
1802907-93-2
Available Sizes
Curated Selection
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