BGC-20-1531 (free base)
BGC-20-1531 (PGN 1531) free base is a potent and selective prostanoid EP4 receptor antagonist, with a pKB of 7.6. BGC-20-1531 free base has the potential for the research of migraine headache[1].
Product Specifications
CAS Number
[736183-35-0]
Product Name Alternative
PGN 1531 (free base)
UNSPSC
12352005
Target
Prostaglandin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/bgc-20-1531-free-base.html
Purity
98.05
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
O=C(C1=CC(COC2=CC=C(C3=NC=C(OC)C=C3)C=C2)=C(C)O1)NS(=O)(C4=CC=CC=C4C)=O
Molecular Formula
C26H24N2O6S
Molecular Weight
492.54
References & Citations
[1]Maubach KA, et al. BGC20-1531, a novel, potent and selective prostanoid EP receptor antagonist: a putative new treatment for migraine headache. Br J Pharmacol. 2009;156 (2) :316-327.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
EP
Available Sizes
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