BGC-20-1531 (free base)

BGC-20-1531 (PGN 1531) free base is a potent and selective prostanoid EP4 receptor antagonist, with a pKB of 7.6. BGC-20-1531 free base has the potential for the research of migraine headache[1].

Product Specifications

CAS Number

[736183-35-0]

Product Name Alternative

PGN 1531 (free base)

UNSPSC

12352005

Target

Prostaglandin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/bgc-20-1531-free-base.html

Purity

98.05

Solubility

DMSO : 250 mg/mL (ultrasonic)

Smiles

O=C(C1=CC(COC2=CC=C(C3=NC=C(OC)C=C3)C=C2)=C(C)O1)NS(=O)(C4=CC=CC=C4C)=O

Molecular Formula

C26H24N2O6S

Molecular Weight

492.54

References & Citations

[1]Maubach KA, et al. BGC20-1531, a novel, potent and selective prostanoid EP receptor antagonist: a putative new treatment for migraine headache. Br J Pharmacol. 2009;156 (2) :316-327.