Mesothelin Recombinant Rabbit Monoclonal Antibody [PSH02-30]
This gene encodes a preproprotein that is proteolytically processed to generate two protein products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
Product Specifications
Product Name Alternative
Abbreviation
MSLN, MPF
Swiss Prot
Q13421 Human
Cellular Locus
Cell membrane, Golgi apparatus; Secreted.
Host
Rabbit
Species Reactivity
Human
Immunogen
Recombinant protein within human Mesothelin aa 273-622 / 622 (Q13421-3).
Isotype
IgG
Clone
PSH02-30
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IF-Cell, IF-Tissue, IHC-P
Positive Control
SiHa cell lysate, NCI-H226 cell lysate, HeLa cell lysate, NIH:OVCAR-3 cell lysate, NCI-H226, human ovarian carcinoma tissue, human tonsil tissue.
Concentration
1 mg/mL
Dilution
WB: 1:1,000 ;IF-Cell: 1:100 ;IF-Tissue: 1:100 ;IHC-P: 1:1,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 68 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes
CAS Number
9000-83-3
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
