Ferret CCL16 Recombinant Protein

The Ferret CCL16 yeast-derived recombinant protein is not tagged and is naturally endotoxin-free. The purity is greater than 98% as visualized by SDS-PAGE analysis. Ferret CCL16 applications are for cell culture, ELISA standard, and Western Blot Control. Ferret CCL16 yeast-derived recombinant protein can be purchased in multiple sizes. Ferret CCL16 Specifications: (Molecular Weight: 9.9 kDa) (Amino Acid Sequence: QSKSPASLNS SHTCCLKHHE KVMPRKMVVG YRRALNCYLP AIIFVTKKNR EICANPQNKW VQEYLRDPNI PLLPPRNLAQ ARSVRP (86) ) (Gene ID: 101674669) . For research use only.

Product Specifications

Background

CCL16, also know as, Liver-expressed chemokine (LEC) and Monotactin-1 (MTN-1) is a member of the CC chemokine family. CCL16 is expressed by the liver, thymus, and spleen and is chemoattractive for monocytes and lymphocytes. Cellular expression of CCL16 can be strongly induced in monocytes by IL-10, IFN-γ and bacterial lipopolysaccharide. CCL16 elicits its effects on cells by interacting with cell surface chemokine receptors such as CCR1, CCR2, CCR5 and CCR8. CCL16 has been found in high levels in the blood plasma of humans. CCL16 may be useful for trafficking eosinophils. This ligand has been found to have a functional affinity for H4 receptors that are expressed by eosinophils and mast cells. This chemokine has been shown to suppress rapid proliferation of myeloid progenitor cells.