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Mouse IL-18 Recombinant Protein

The Mouse IL-18 yeast-derived recombinant protein is not tagged and is naturally endotoxin-free. The purity is greater than 98% as visualized by SDS-PAGE analysis. Mouse IL-18 applications are for cell culture, ELISA standard, and Western Blot Control. The Mouse IL-18 yeast-derived recombinant protein can be purchased in multiple sizes. Mouse IL-18 Specifications: (Molecular Weight: 18.1 kDa) (Amino Acid Sequence: NFGRLHCTTA VIRNINDQVL FVDKRQPVFE DMTDIDQSAS EPQTRLIIYM YKDSEVRGLA VTLSVKDSKM STLSCKNKII SFEEMDPPEN IDDIQSDLIF FQKRVPGHNK MEFESSLYEG HFLACQKEDD AFKLILKKKD ENGDKSVMFT LTNLHQS (157) ) (Gene ID: 16173) . For research use only.

Product Specifications

Background

Interleukin 18 (IL-18), also know an IL-1F4, was isolated as a co-factor that, in synergism with IL-12, stimulated the production of IFN gamma in Th1 cells. It is now understood that IL-18 is an important link between innate and adaptive immune responses and a regulator of both cellular and humoral immunity. IL-18 is secreted in its active form following cleavage by caspase 1 in response to inflammatory and infectious stimuli. In addition to its effects on Th1 cells, IL-18 is a strong stimulator of the activity of natural killer cells alone or in combination with IL-15, and of CD8+ lymphocytes. Together with IL-2, IL-18 can also stimulate the production of IL-13 and of other Th2 cytokines. IL-18 plays a role in numerous inflammatory-associated disorders.

Sequence

NFGRLHCTTA VIRNINDQVL FVDKRQPVFE DMTDIDQSAS EPQTRLIIYM YKDSEVRGLA VTLSVKDSKM STLSCKNKII SFEEMDPPEN IDDIQSDLIF FQKRVPGHNK MEFESSLYEG HFLACQKEDD AFKLILKKKD ENGDKSVMFT LTNLHQS (157)

Applications

Cell Culture, ELISA Standard, ELISpot Control, Western Blot Control

Homology

Mus musculus (house mouse)

Endotoxin

Naturally endotoxin-free

Purity

>98% as visualized by SDS-PAGE analysis.

Molecular Weight

18.1 kda

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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