Human BAFF Recombinant Protein

The Human BAFF yeast-derived recombinant protein is not tagged and is naturally endotoxin-free. The purity is greater than 98% as visualized by SDS-PAGE analysis. Human BAFF applications are for cell culture, ELISA standard, and Western Blot Control. Human BAFF yeast-derived recombinant protein can be purchased in multiple sizes. Human BAFF Specifications: (Molecular Weight: 17.0 kDa) (Amino Acid Sequence: AVQGPEETVT QDCLQLIADS ETPTIQKGSY TFVPWLLSFK RGSALEEKEN KILVKETGYF FIYGQVLYTD KTYAMGHLIQ RKKVHVFGDE LSLVTLFRCI QNMPETLPNN SCYSAGIAKL EEGDELQLAI PRENAQISLD GDVTFFGALK LL (152) ) (Gene ID: 10673) . For research use only.

Product Specifications

Background

BAFF (B-cell Activation Factor), also know as Tumor Necrosis Factor Superfamily member 13B is a member of the tumor necrosis factor ligand (TNF) ligand family. Nineteen cytokines have been identified as part of the TNF family on the basis of sequence, functional, and structural similarities. Family members include TNF beta (TNFSF1), TNF alpha, Lymphotoxin beta (TNFSF3), OX40 Ligand (TNFSF4), CD40 Ligand (TNFSF5), Fas Ligand (TNFSF6), CD27 Ligand (TNFSF7), CD30 Ligand (TNFSF8), 4-1BB Ligand (TNFSF9), TRAIL (TNFSF10), TRANCE/RANKL (TNFSF11), TWEAK (TNFSF12), APRIL (TNFSF13), BAFF, LIGHT (TNFSF14), TL1A/VEGI (TNFSF15), and GITR Ligand (TNFSF18) . BAFF is expressed in B cell lineage cells, and acts as a potent B cell activator. It has been also shown to play an important role in the proliferation and differentiation of B cells.

Sequence

AVQGPEETVT QDCLQLIADS ETPTIQKGSY TFVPWLLSFK RGSALEEKEN KILVKETGYF FIYGQVLYTD KTYAMGHLIQ RKKVHVFGDE LSLVTLFRCI QNMPETLPNN SCYSAGIAKL EEGDELQLAI PRENAQISLD GDVTFFGALK LL (152)

Applications

Cell Culture, ELISA Standard, ELISpot Control, Western Blot Control

Homology

Homo sapiens (human), Pan paniscus (pygmy chimpanzee), Pan troglodytes (chimpanzee), Pongo abelii (Sumatran orangutan), Pongo pygmaeus (Bornean orangutan)