Human TNF alpha Recombinant Protein

The Human TNF alpha yeast-derived recombinant protein is not tagged and is naturally endotoxin-free. The purity is greater than 98% as visualized by SDS-PAGE analysis. Human TNF alpha applications are for cell culture, ELISA standard, and Western Blot Control. The Human TNF alpha yeast-derived recombinant protein can be purchased in multiple sizes. Human TNF alpha Specifications: (Molecular Weight: 17.2 kDa) (Amino Acid Sequence: VRSSSRTPSD KPVAHVVANP QAEGQLQWLN RRANALLANG VELRDNQLVV PSEGLYLIYS QVLFKGQGCP STHVLLTHTI SRIAVSYQTK VNLLSAIKSP CQRETPEGAE AKPWYEPIYL GGVFQLEKGD RLSAENRPDY LDFAESGQVY FGIIAL (156) ) (Gene ID: 7124) . For research use only.

Product Specifications

Background

TNF alpha is a member of the TNF Superfamily. It is produced chiefly by activated macrophages, but it is produced also by a broad variety of cell types including lymphoid cells, mast cells, endothelial cells, cardiac myocytes, adipose tissue, fibroblasts, and neuronal tissue. The primary role of TNF alpha is in the regulation of immune cells. TNF alpha, being an endogenous pyrogen, is able to induce fever, to induce apoptotic cell death, to induce sepsis (through IL-1 & IL-6 production), to induce cachexia, induce inflammation, and to inhibit tumorigenesis and viral replication.

Applications

Cell Culture, ELISA Standard, ELISpot Control, Western Blot Control

Homology

Gorilla gorilla gorilla (western lowland gorilla) [Ile135/136Deletion], Homo sapiens (human) [Ile135/136Deletion], Pan paniscus (pygmy chimpanzee) [Ile135/136Deletion], Pan troglodytes (chimpanzee) [Ile135/136Deletion]