Bovine Fas Ligand (TNFSF6) Recombinant Protein

The Bovine Fas Ligand yeast-derived recombinant protein is not tagged and is naturally endotoxin-free. The purity is greater than 98% as visualized by SDS-PAGE analysis. Bovine Fas Ligand applications are for cell culture, ELISA standard, and Western Blot Control. Bovine Fas Ligand yeast-derived recombinant protein can be purchased in multiple sizes. Bovine Fas Ligand Specifications: (Molecular Weight: 17.3 kDa) (Amino Acid Sequence: QIGHPSPPSE KKELKKAAHL TGKLNSRSIP LEWEDTYGIA LVSGVKYKKG SLVINETGLY FVYSKVYFRG QSCNNQPLSH KVYSRNFRYP QDMVLMEGKM MNYCTSGKMW ARSSYLGAVF NLTSADHLYV NVSELSLVSF EESKTFFGLY KL (152) ) (Gene ID: 407111) . For research use only.

Product Specifications

Background

Fas ligand, also known as CD95L and TNFSF6, is a homotrimeric type II transmembrane protein belonging to the tumor necrosis factor (TNF) superfamily. FasL plays diverse roles in the immune system, including induction of apoptotic cell death in target cells. FasL-Fas-mediated apoptosis plays fundamental roles in several immune functions. The pathway is involved in functions including regulation of T cell homeostasis and maintenance of immune privilege, apart from its well-established role in T cell-mediated cytotoxicity. Cytotoxicity via the Fas pathway is critical for prevention of pathogenic infections as well as control of tumor cell growth