Multi-species (Ovine, Caprine) M-CSF Recombinant Protein

The Ovine & Caprine M-CSF yeast-derived recombinant protein is not tagged and is naturally endotoxin-free. The purity is greater than 98% as visualized by SDS-PAGE analysis. Ovine & Caprine M-CSF applications are for cell culture, ELISA standard, and Western Blot Control. Ovine & Caprine M-CSF yeast-derived recombinant protein can be purchased in multiple sizes. Ovine & Caprine M-CSF Specifications: (Molecular Weight: 18.0 kDa) (Amino Acid Sequence: EEVSENCSHM IGNGHLLFLQ QLIDSQMETS CQISFEFVDQ EQLDDPVCYL KKAFLLVQDI MEDTMRFKDN TPNAKAIVQL QELSLRLKSC FTMDYDEQDK ACVRTFHETP LQLLEKIKNV FNETKNLLKK DWNVFSKNCN NSFAKCSSHG HERQ (154) ) (Gene ID: 102185051 (Caprine) ; 101104200 (Ovine) ) . For research use only.

Product Specifications

Background

M-CSF (Macrophage colony-stimulating factor), also known as CSF-1, is a hematopoietic growth factor that is involved in the proliferation, differentiation, and survival of monocytes, macrophages, and bone marrow progenitor cells. M-CSF enhances expression of differentiation antigens and stimulates chemotactic, phagocytic and the killing activities of monocytes. M-CSF also stimulates production of several cytokines, including GM- CSF, G-CSF and IL-6 by priming monocytes. It also stimulates production and secretion of IL-8 and reactive nitrogen intermediates. In addition to the stimulation of hematopoiesis, M-CSF also stimulates differentiation and proliferation of osteoclast progenitor cells and cytotrophoblasts.