Mouse IL-34 Recombinant Protein

The Mouse IL-34 yeast-derived recombinant protein is not tagged and is naturally endotoxin-free. The purity is greater than 98% as visualized by SDS-PAGE analysis. Mouse IL-34 applications are for cell culture, ELISA standard, and Western Blot Control. The Mouse IL-34 yeast-derived recombinant protein can be purchased in multiple sizes. Mouse IL-34 Specifications: (Molecular Weight: 24.6 kDa) (Amino Acid Sequence: NENLEIWTLT QDKECDLTGY LRGKLQYKNR LQYMKHYFPI NYRIAVPYEG VLRVANITRL QKAHVSEREL RYLWVLVSLN ATESVMDVLL EGHPSWKYLQ EVQTLLENVQ RSLMDVEIGP HVEAVLSLLS TPGLSLKLVR PKALLDNCFR VMELLYCSCC KQSPILKWQD CELPRLHPHS PGSLMQCTAT NVYPLSRQTP TSLPGSPSSS HGSLP (215) ) (Gene ID: 76527) . For research use only.

Product Specifications

Background

IL-34 is a homodimeric cytokine identified by high throughput screening of human recombinant secreted factors. It contains no known conserved domains and has no sequence homology with other cytokines. IL-34 is recognized by colony-stimulating factor 1 receptor (CSF-1R) . CSF-1R also binds M-CSF. Both IL-34 and M-CSF are involved in the survival, proliferation and differentiation of mononuclear phagocytes, including monocytes, macrophages, dendritic cells, Langerhans cells, microglia and osteoclasts.