Swine C3a Recombinant Protein

The Swine C3a yeast-derived recombinant protein is not tagged and is naturally endotoxin-free. The purity is greater than 98% as visualized by SDS-PAGE analysis. Swine C3a applications are for cell culture, ELISA standard, and Western Blot Control. Swine C3a yeast-derived recombinant protein can be purchased in multiple sizes. Swine C3a Specifications: (Molecular Weight: 9.1 kDa) (Amino Acid Sequence: SVQLMEKRMD KLGQYSKDVR RCCEHGMRDN PMKFSCQRRA QFIQHGDACV KAFLDCCEYI AKLRQQHSRN KPLGLAR (77) ) (Gene ID: 397072) . For research use only.

Product Specifications

Background

C3a is an effector molecule of both the classical and alternative complement pathways for a broad range of functions including T cell activation and survival, angiogenesis stimulation, chemotaxis, mast cell degranulation, and macrophage activation. C3a produces both pro- and anti-inflammatory responses. The binding of C3a to the specific G protein-coupled receptor, C3aR, has been shown to be involved in several diseases such as rheumatoid arthritis, septic shock syndrome, age-related macular degeneration, and asthma. The immune response, initiated by C3a, acts by stimulating mast cell degranulation.